Hypoxia Inducible Factor-1# in Astrocytes- and/or Myeloid Cells is not Required for the Development of Autoimmune Demyelinating Disease Cell-Specific Roles of HIF-1# in EAE
نویسندگان
چکیده
This work was supported by a National Multiple Sclerosis Society postdoctoral fellowship to N.L.M. and NIH/ NINDS grants R01NS051470 and R01NS052189 to K.A. V.A.R is an American Heart Association (AHA) postdoctoral fellow and D.D. holds Scientist Development Grant 13SDG17210051 from AHA. The J. David Gladstone Institutes received support from a National Center for Research Resources (grant RR18928).
منابع مشابه
Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease
Hypoxia-like tissue alterations, characterized by the upregulation of hypoxia-inducible factor-1α (HIF-1α), have been described in the normal appearing white matter and pre-demyelinating lesions of multiple sclerosis (MS) patients. As HIF-1α regulates the transcription of a wide set of genes involved in neuroprotection and neuroinflammation, HIF-1α expression may contribute to the pathogenesis ...
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Hypoxia-like tissue alterations, characterized by the upregulation of hypoxia-inducible factor-1α (HIF-1α), have been described in the normal appearing white matter and pre-demyelinating lesions of multiple sclerosis (MS) patients. As HIF-1α regulates the transcription of a wide set of genes involved in neuroprotection and neuroinflammation, HIF-1α expression may contribute to the pathogenesis ...
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تاریخ انتشار 2015